Antibacterial Silver Loaded Hydroxyapatite Coating Prepared Through the Reduction of Phytic Acid-Silver Ion Complex

QuanxinWang, Jianbin Luoa,Chunmei Dingb

Hydroxyapatite coating was built on the surface of materialsby mineralization of phytic acid-metallic ion complex, whichfurther absorbed surplus phytic acidon the outer layer. Then, silver ions were stabilizedbased on their chelation with phytic acid. Finally, we obtained silver-loaded hydroxyapatite coating when the silver ions were reduced to nano silver particles under the effect of glucose. The successful loading of silver particles were proved by scanning electron microscopy, Raman and EDS measurement. This coating exhibited broad antibacterial properties against Escherichia coli (gram negative bacteria) and Staphylococcus aureus (gram positive bacteria). The antibacterial hydroxyapatite coating developed here might have potential applications in the area of biomedical, such as bone and dental implant.