Clinical Review on the Main Pathologies Related To the Nuclear Envelope

Herica Morais da Silva, Dara Dos Santos Souza, Magno De Oliveira, Wolney Jácomo, Isabela Maria Agustini da Silveira Bastos, Augustus Caeser Franke Portella, Talita Pereira de Sousa Ferreira, Dalmarcia de Souza Carlos Mourão, Marcos Vinicius Giongo Alves, Aloísio Freitas Chagas Junior

The study on the nuclear envelope has become of great importance in scientific research in a multidisciplinary way. The nuclear blade gains more space in research for having a directrelation ship in the development of a typical genetic diseases, attributed as laminopathies. Nuclear laminaria have architecture with diverse attributions, consequently grants mechanical and support actions, stabilizes and organizes the chromatin, during the process of DNA replication, RNA synthesis and the balance of gene expression. These multiplicities of processes denote that genetical terations influence with great expression, as can beseen in Laminopathies.The methods used for this work were based on the methodology of the article Experimental Planning Factorial: Abrief Review of (OLIVEIRA et al., 2018). As a result of the studies made, a wide range of diseases, little known, was mad eexplicit. That previously had hardly their roots of emergence associated with apart, considered untilth enlittle important in the scientifics cope of the cellular studies, like the Nuclear envelope. In this way, one can attribute the emergence of distinct pathologies, which are manifested in different parts of the body, including muscular, cardiovascular, subcutaneousa diposetissue among others. With such advances on the nuclear envelope, and on its importance in disease development, there is the opportunity of discoveries of new forms of medical treatments and prevention methods (possible), this realistic basis is toosubstantial.

https://doi.org/10.31871/IJNTR.5.5.8